Junior Specialist - Ramani Lab

Junior Specialist - Ramani Lab

The laboratory of Dr. Biswa Ramani (Department of Pathology and Division of Neuropathology) is seeking a Junior Research Specialist to join our team, dedicated to uncovering modifiers of protein aggregation and neuronal loss across various neurodegenerative disorders, including Huntington's disease (and related disorders), frontotemporal dementia, and amyotrophic lateral sclerosis. Our research utilizes cutting-edge CRISPR-based functional genomics tools in combination with cell and animal models to uncover novel insights. We integrate these tools with flow cytometry, imaging, biochemical, transcriptomic, and proteomic approaches to understand disease mechanisms.

Key responsibilities may include:

• Conducting molecular biology experiments, including PCR, plasmid preparation, and cloning.
• Performing basic mammalian cell culture for viral vector packaging and purification.
• Handling and performing procedures on mice for genotyping and in vivo studies.
• Processing and preparation of mouse brain tissues for imaging studies.
• Maintaining records of experimental protocols and findings along with contributing to data analysis.
• Participate in shared lab responsibilities, such as ordering, organizing, and shipping supplies and regents.

Required Qualifications:

• Specialists appointed at the junior rank must possess a bachelor's degree (or equivalent degree) or have least four years of relevant research experience, by the time of hire.
• Must have previous research experience.
• Excellent organizational and analytical skills.
• Excellent interpersonal communication (verbal and written).
• Ability to work independently, prioritize and coordinate tasks, and meet multiple deadlines.
• Applicants' materials must list current and/or pending qualifications upon submission.

Preferred Qualifications:

• Experience with tissue culture and cell biology.
• Experience with molecular biology, including PCR, cloning, and plasmid preparation.
• Experience with basic handling of mice for separating weanlings.
• Experience with histology, including processing, embedding, and sectioning of frozen or FFPE tissues.

See Table 24B for the salary range for this position. A reasonable estimate for this position is $53,100 - $56,600.

Please apply online at https://aprecruit.ucsf.edu/JPF05386.

• 3 required (contact information only)

As a University employee, you will be required to comply with all applicable University policies and/or collective bargaining agreements, as may be amended from time to time. Federal, state, or local government directives may impose additional requirements.

The University of California is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age, protected veteran status, or other protected status under state or federal law.

As a condition of employment, the finalist will be required to disclose if they are subject to any final administrative or judicial decisions within the last seven years determining that they committed any misconduct.

* "Misconduct" means any violation of the policies or laws governing conduct at the applicant's previous place of employment, including, but not limited to, violations of policies or laws prohibiting sexual harassment, sexual assault, or other forms of harassment, or discrimination, as defined by the employer.

* UC Sexual Violence and Sexual Harassment Policy

* UC Anti-Discrimination Policy

* APM - 035: Affirmative Action and Nondiscrimination in Employment