New

Interactome Staff Scientist

California Institute of Technology
vision insurance, parental leave, paid time off, sick time, tuition reimbursement
United States, California, Pasadena
Feb 27, 2025
Caltech is a world-renowned science and engineering institute that marshals some of the world's brightest minds and most innovative tools to address fundamental scientific questions. We thrive on finding and cultivating talented people who are passionate about what they do. Join us and be a part of the diverse Caltech community. Job Summary The person in the position will oversee functional screens of the global human cell-surface interactome project. Using cell based high-throughput screening as well as specifically designed tests for selected ligand-receptor pairs, they will provide insight to biological significance of the novel interactions discovered in the interactome. Essential Job Duties The person in position will: Carry out cell surface binding assay of the full cell-surface extracellular domain (ECD) library to human primary cells (25%) Single-cell RNA sequencing for the transcriptional response of the human primary cells when incubated with the ECD library (40%) Function analysis designed for specific ligand-receptor pairs in receptor KO cell lines (35%). Basic Qualifications The position requires a: PhD in Biology and three years of training post receiving the degree. Have a strong background in molecular biology and cell biology and must be BSL2 trained. Preferred Qualifications The person in position is preferred to: Be trained in human primary cells handling, experience with human peripheral blood mononuclear cells (PBMCs) is ideal. Use flow cytometer and analyze flow cytometry data. Experience in single-cell sequencing assays as well as bioinformatics for analyzing sequencing data. Required Documents Resume. Hiring Range $60,000 - $82,500 Per Year The salary of the finalist(s) selected for this role will be set based on a variety of factors, including but not limited to, internal equity, experience, education, specialty and training. As one of the largest employers in Pasadena, CA, Caltech is committed to providing comprehensive benefits to eligible employees and their eligible dependents. Our benefits package includes competitive compensation, health, dental, and vision insurance, retirement savings plans, generous paid time off (vacation, holidays, sick time, parental leave, bereavement, etc.), tuition reimbursement, and more. Non-benefit eligible employees will have access to some benefits such as onsite counseling and sick time. Learn more about our benefits and staff perks. EEO Statement We are an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to age, race, color, religion, sex, sexual orientation, gender identity, or national origin, disability status, protected veteran status, or any other characteristic protected by law. Caltech is a VEVRAA Federal Contractor. To read more Equal Employment Opportunity (EEO) go to eeoc_self_print_poster.pdf. Disability Accommodations If you would like to request an accommodation in completing this application, interviewing, or otherwise participating in the employee selection process, please direct your inquiries to Caltech Recruiting at employment@caltech.edu.