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Bioinformatics Analyst, Cancer Center (Rheinbay & Ellisen Lab)

Massachusetts General Hospital
United States, Massachusetts, Boston
149 13th Street (Show on map)
Mar 05, 2025
The MGH Center for Cancer Research is looking for a bioinformatics analyst to study genomics and epigenomics of breast cancer. The general focus of the project is intra-tumoral heterogeneity of breast cancer and specifically triple-negative breast cancer, as well as the genetic and epigenetic underpinnings of these cancers that affect outcomes and response to therapy. We also have a special interest in the molecular differences in tumor biology in women of different ancestry that contribute to worse outcomes in certain populations. This position is a joint appointment between the laboratory of Dr. Leif Ellisen, Breast Oncology Program Director, and the Cancer Center's computational group led by Drs. Esther Rheinbay and Michael Lawrence. The successful candidate will join an interdisciplinary team working on rigorous analysis of next generation sequencing data (DNA, RNA, chromatin, single-cells) from tumor and normal samples.
The ideal candidate has a strong background in computation, actively seeks out solutions to challenges and enjoys working in small teams.
https://ellisenlab.com/
https://www.massgeneral.org/cancer-center/clinical-trials-and-research/center-forcancer-
research/investigators/rheinbay-lab
https://www.massgeneral.org/cancer-center/clinical-trials-and-research/center-forcancer-
research/investigators/lawrence-lab

Education

Master's Degree Computational Biology preferred or

Bachelor's Degree Computational Biology required

Can this role accept experience in lieu of a degree? Yes

Experience

Computational Sciences Experience 0-1 year preferred

Knowledge, Skills & Abilities

Demonstrated experience in infrastructure, programming languages and computational sciences.

Demonstrated ability working with open-source bioinformatics software.

Possess strong analytical skills including critical thinking, data modeling, problem solving and troubleshooting.

Strong organizational and interpersonal skills.

Ability to effectively communicate, both orally and in writing, to all levels of staff.

Excellent time management skills.

The General Hospital Corporation is an Equal Opportunity Employer. By embracing diverse skills, perspectives and ideas, we choose to lead. All qualified applicants will receive consideration for employment without regard to race, color, religious creed, national origin, sex, age, gender identity, disability, sexual orientation, military service, genetic information, and/or other status protected under law. We will ensure that all individuals with a disability are provided a reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment.
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