Rsch Pro 1-Preclinical Rsch - Department of Neuroscience

Our laboratory is currently seeking a Researcher 1 to help assist with projects focused on mechanisms of neurodegeneration in the context of demyelinating diseases such as multiple sclerosis. They will be trained and perform a wide range of cell and molecular biology techniques facilitating the acquisition of data for publications and NIH grant applications. The projected start date for this position is in mid to late September.

Job Duties and Responsibilities:
(These examples do not include all possible tasks in this work and do not limit the assignment of related tasks)

80% Research and data analysis:
* Learn and perform all aspects of immunohistochemical analysis for protein expression of tissue including tissue dissection, sectioning, staining and imaging using fluorescent microscopy and subsequent manual or automated analyses.
* Perform fluorescent in situ hybridization of relevant RNA transcripts in tissue
* Mouse colony management and husbandry, intraperitoneal and intravitreous injections
* Learn and employ a wide variety of molecular biology techniques including subcloning of novel plasmids for in vitro use or AAV production, DNA and RNA extractions, PCR and gel electrophoresis for genotyping, tissue culture of neuronal stem cells, and Western blot analyses.
* Basic coding to analyze single-nuclei RNA sequencing datasets in R using Seurat
* Select and adapt methods to meet their specific research needs and to assist in development of new laboratory techniques.
* Maintain a detailed notebook, tabulate and graph data, and interpret results

20% Research Support:
* Involved in the operation and maintenance of equipment, data management, ensuring lab safety, and ordering necessary supplies and reagents
* Preparation of solutions and buffers, hazardous waste management and laboratory organization
* Assistance with intracranial surgeries in mice
* Keep records of protocols and laboratory standard operating procedures
* Assistance in the preparation of data for manuscripts and grants.

Required Qualifications
* Bachelor's degree in a relevant discipline (cell biology, neuroscience, biochemistry, genetics, etc) or a combination of education and relevant work experience to equal at least four years.
* Previous experience working in a laboratory.
* A proactive person with strong organizational and communications skills who is able to work as part of a team.

Preferred Qualifications
* At least one year of relevant research experience
* Experience with fluorescence microscopy or transmission electron microscopy
* Laboratory experience with common cell and molecular biology techniques including molecular cloning, western blots, PCR and gel electrophoresis, cell culturing etc.
* Experience handling and working with rodents (mice)
* Bioinformatics experience, particularly analyzing RNA sequencing datasets would be an asset

Neuroscience is the scientific study of the nervous system. It is an interdisciplinary science that collaborates with other fields such as chemistry, computer science, engineering, linguistics, mathematics, medicine and allied disciplines, philosophy, physics, and psychology.

The Department of Neuroscience is committed to providing excellence in research, education, and public service. The Department of Neuroscience is part of the University of Minnesota's Medical School.

Pay Range: $21.61 - $26.23 per hour; depending on education/qualifications/experience

Time Appointment Category: 75%-100% Appointment (If job description above does not specify appointment or expected weekly hours, assume a 100% appointment.)

Position Type: Civil-Service & Non-Faculty Labor Represented Staff

Please visit the Office of Human Resources website for more information regarding benefit eligibility.

The University offers a comprehensive benefits package that includes:

• Competitive wages, paid holidays, and generous time off
• Continuous learning opportunities through professional training and degree-seeking programs supported by the Regents Tuition Benefit Program
• Low-cost medical, dental, and pharmacy plans
• Healthcare and dependent care flexible spending accounts
• University HSA contributions
• Disability and employer-paid life insurance
• Employee wellbeing program
• Excellent retirement plans with employer contribution
• Public Service Loan Forgiveness (PSLF) opportunity
• Financial counseling services
• Employee Assistance Program with eight sessions of counseling at no cost
• Employee Transit Pass with free or reduced rates in the Twin Cities metro area

Applications must be submitted online. To be considered for this position, please click the Apply button and follow the instructions. You will be given the opportunity to complete an online application for the position and attach a cover letter and resume.

Additional documents may be attached after application by accessing your "My Job Applications" page and uploading documents in the "My Cover Letters and Attachments" section.

To request an accommodation during the application process, please e-mail employ@umn.edu or call (612) 624-8647.

The University recognizes and values the importance of diversity and inclusion in enriching the employment experience of its employees and in supporting the academic mission. The University is committed to attracting and retaining employees with varying identities and backgrounds.

The University of Minnesota provides equal access to and opportunity in its programs, facilities, and employment without regard to race, color, creed, religion, national origin, gender, age, marital status, disability, public assistance status, veteran status, sexual orientation, gender identity, or gender expression. To learn more about diversity at the U: http://diversity.umn.edu

Any offer of employment is contingent upon the successful completion of a background check. Our presumption is that prospective employees are eligible to work here. Criminal convictions do not automatically disqualify finalists from employment.

The University of Minnesota, Twin Cities (UMTC)

The University of Minnesota, Twin Cities (UMTC), is among the largest public research universities in the country, offering undergraduate, graduate, and professional students a multitude of opportunities for study and research. Located at the heart of one of the nation's most vibrant, diverse metropolitan communities, students on the campuses in Minneapolis and St. Paul benefit from extensive partnerships with world-renowned health centers, international corporations, government agencies, and arts, nonprofit, and public service organizations.

At the University of Minnesota, we are proud to be recognized by the Star Tribune as a Top Workplace for 2021, as well as by Forbes as Best Employers for Women and one of America's Best Employers (2015, 2018, 2019, 2023), Best Employer for Diversity (2019, 2020), Best Employer for New Grads (2018, 2019), and Best Employer by State (2019, 2022).