Endpoint Senior Engineer - Comprehensive Cancer Center

The Endpoint Senior Engineer plays a critical role in supporting the mission of advancing cancer research and patient care through robust, high-availability IT infrastructure. This role provides advanced, on-site and remote support for a wide range of technologies across Windows, macOS, and Linux platforms while ensuring compliance with cybersecurity, data integrity, and institutional IT policies across research labs, clinical environments, and data-intensive computing areas. The engineer will be deeply involved in deploying, maintaining, and securing computing environments used in high-throughput biological research, genomics, imaging, and patient data analytics. Operating within a dynamic, multi-disciplinary cancer research ecosystem, this position ensures end-to-end support for essential systems that power discovery, collaboration, and clinical translation.

Key Responsibilities

• Provide high-level support for workstations running Windows, macOS, and Linux operating systems across laboratories, shared research facilities, administration areas, and specialized cancer research units.
• Collaborate with researchers, clinicians, administrators and IT colleagues to ensure infrastructure aligns with evolving cancer research requirements including large data set analysis, high-performance computing, imaging, and genomics.
• Serve as a liaison between central IT and laboratory end users, working on complex technical issues, recommending sustainable solutions, and documenting troubleshooting procedures.
• Support network connectivity for high-throughput instruments, lab automation systems, and clinical research applications; coordinate with network engineering to resolve bandwidth or access issues.
• Participate in the planning and execution of IT infrastructure projects supporting lab expansion, relocations, and technology refresh initiatives.
• Maintain compliance with institutional security policies and external standards (HIPAA, NIST 800-171, ISO 27001), especially for environments processing PHI or research subject data.
• Maintain strong awareness of compliance requirements including HIPAA, data retention policies, and cybersecurity best practices in research environments.
• Mentor junior staff and students and support the development of standard operating procedures and knowledge-sharing practices within the field services team.
• Provide advanced troubleshooting for field-deployed systems, including:
  • Domain integration
  • Certificate and keychain issues
  • Driver and hardware failures
  • OS patching and imaging
• Configure and manage MDM platforms (e.g., SCCM, JAMF) and remote support tools (e.g., TeamViewer).
• Work closely with researchers and IT architects to support secure deployments of high-performance computing (HPC), microscopy, sequencing, or AI-driven diagnostic tools.
• Lead or assist in secure device deployments, migrations, decommissions, and lab buildouts or renovations.
  

Minimum Qualifications

• Education
  
• Bachelors degree in computer science, Information Technology, Engineering, or a related disciplineor equivalent combination of education and experience.
  
• Experience
  • Minimum 4 years of relevant experience in IT field support.
  • Preferred: 612 years, including experience supporting diverse computing environments in academic, healthcare, or biomedical research settings.
    
• Technical Proficiency
  • Advanced expertise in troubleshooting and maintaining Windows 10/11, macOS, and various Linux distributions.
  • Experience with lab-specific hardware and software (e.g.,Zeiss, Nikon, Vectra, EVOS,Leica, and Olympus microscopes and cameras;Thermo Fisher: Genexus, iBright, TAC; TapeStations, 2100 Expert, Nano Drop; Licor equipment and Image Studio software; Azure Sapphire, Cielo qPCR Machines, Kaluza, FlowJo, Setarious Incucyte equipment and software etc. ) and support of networked scientific equipment.
  • Proficiency with data analysis tools and languages such as Python and R for troubleshooting, reporting, and optimizing endpoint performance.
  • Expert Knowledge of Active Directory, group policy, secure shell (SSH), endpoint encryption, and remote support tools.
  • Familiarity with ITSM tools (e.g., ServiceNow), inventory and asset management using Workday, and patch/update practices across OS platforms.
  • Security: Hands-on experience with EDR tools (e.g., CrowdStrike, Defender DLP), vulnerability scanning, patch compliance, disk encryption, MFA, and group policy management.
  • Proficient in SCCM, JAMF, Active Directory, Group Policy, SSH, Bash/PowerShell scripting, and RDP/ARD.
    

Preferred Qualifications

• Experience working in cancer research or healthcare IT environment.
• Understanding of regulatory frameworks such as HIPAA, 21 CFR Part 11, and NIH/NCI compliance expectations.
• Familiarity with support for virtualization technologies, container environments, or HPC clusters is a plus.
  

Key Competencies

• Strong communication and interpersonal skills, with the ability to work effectively in interdisciplinary teams.
• An analytical and problem-solving mindset; able to adapt quickly to evolving research and clinical priorities.
• Self-motivated with demonstrated ability to lead initiatives and manage multiple priorities in a fast-paced setting.
• Committed to supporting innovation and excellence in cancer research through responsive and resilient IT service delivery.
  

Function/Sub-Function: Information Technology/Endpoint Engineering

Career Band: Individual Contributor - Specialized

Career Level: S3