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Associate Director, Pain Forecasting

Vertex Pharmaceuticals Incorporated
paid time off, 401(k)
United States, Massachusetts, Boston
50 Northern Avenue (Show on map)
Oct 08, 2025

Job Description

General Summary:

Vertex is seeking to hire a Associate Director, Pain Forecasting to join the North America Forecasting, Analytics and Market Research team in the Commercial organization. This role will provide forecasting support & associated analytics for the ongoing pain launch and any future launches in pain across North America.

The ideal candidate must be a skilled and experienced individual contributor, with a demonstrated ability to develop & maintain complex models using both top-down and bottom-up forecasting techniques. This candidate must possess a high degree of attention to detail and accuracy in creating deliverables and must be self-directed in engaging with colleagues. Additionally, this candidate must be able to strategize, collaborate, and manage relationships with our many cross-functional partners.

Key Duties and Responsibilities:

  • Build, maintain, and continuously improve demand forecast models leveraging top-down and bottom-up approaches to provide an overall forecast and additional detail on depth & breadth of prescribing across customer segments
  • Leverage all available research & analytics from within the team & cross-functionally to create & update forecasting assumptions
  • Work cross-functionally to coordinate / integrate demand forecast models with gross-to-net, market access, and financial models to ensure alignment & consistency of assumptions
  • Leverage forecast models to support demand & financial modeling for new opportunities under evaluation by the BU
  • Ensure outputs of each forecasting period are clearly communicated to downstream processes (e.g. supply chain) and forecasting data is readily available to required stakeholders within the Pain BU
  • Contribute to the advancement of forecasting capabilities at Vertex

Knowledge and Skills:

  • Proficiency with complex excel forecast models, and experience integrating forecast models with other cross-functional models; experience pulling data from a data warehouse to support forecasting (e.g. SQL)
  • Proficiency working with wide array of commercial pharma data sets, including data sets such as IQVIA (or equivalent from different data vendor) XPONENT PlanTrak, DDD, LAAD (patient claims data)
  • Experience forecasting products competing in large, complex markets and experience across both retail & hospital products
  • Strong analytical and business acumen: intellectual curiosity, motivation and ability to structure problems, diagnose issues and triangulate with multiple approaches
  • Experience working with analytics & forecasting leadership to evaluate & pressure-test assumptions and communicate forecasting outputs to business leadership
  • Ability to quickly and thoughtfully adapt to new and evolving business and planning needs

Education and Experience:

  • Bachelor's degree in quantitative discipline required (e.g., Engineering, Statistics, Economics, Finance, Business Analytics) or equivalent experience
  • 7-10 years of experience in the pharmaceutical or biotech industry, 6+ years of insights, forecasting, and/or analytics is required.

Pay Range:

$162,000 - $242,900

Disclosure Statement:

The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law.

At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.

Flex Designation:

Hybrid-Eligible Or On-Site Eligible

Flex Eligibility Status:

In this Hybrid-Eligible role, you can choose to be designated as:
1. Hybrid: work remotely up to two days per week; or select
2. On-Site: work five days per week on-site with ad hoc flexibility.

Note: The Flex status for this position is subject to Vertex's Policy on Flex @ Vertex Program and may be changed at any time.

Company Information

Vertex is a global biotechnology company that invests in scientific innovation.

Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.

Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com

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