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Executive Director, Therapeutic Area Lead, CVRM

Genentech
United States, California, South San Francisco
Dec 17, 2025
The Position

A healthier future. It's what drives us to innovate. To continuously advance science and ensure everyone has access to the healthcare they need today and for generations to come. Creating a world where we all have more time with the people we love.

The Opportunity

The Executive Director, Therapeutic Area Lead plays a meaningful role in leading a team of Medical Directors/Medical Science Directors and/or MD/MSD Manager to develop, deliver, and execute the medical strategy for specific therapeutic areas, advocating the relevant medical perspective to drive progress and serving as a key member of the US Medical (USM) leadership community. They are accountable for the success of the company in key therapeutic areas, bringing deep medical expertise, innovation, and critical thinking to drive strategic planning and execution with a customer-centric approach, while also maintaining a comprehensive understanding of relevant clinical, market, and access landscapes for their assigned therapeutic area and building capabilities in collaboration with key stakeholders.

Key Responsibilities

  • Drive the synthesis and translation of scientific data/clinical situations into strategy and solutions, appreciating and navigating trade-offs within and beyond medical.

  • Proactively bring feasible options for evidence generation, medical communications, and customer engagement, with an understanding of unmet medical needs, and ensure execution aligned with the shared disease area strategy, squad priorities, and integrated customer plan.

  • Partner across CMG, US Medical functions, and with global colleagues to create and deliver options supporting short and long-term goals, providing perspective to avoid redundant efforts and catalyze sound investment decisions.

  • Lead the formation and execution of high-quality Phase IIIb/IV clinical trials and investigator-initiated research, consistently engaging with customers to understand their evolving medical needs and identifying knowledge gaps and opportunities for collaboration.

Who you are

Qualifications & Experience

  • Post-graduate degree required (e.g. MD, PhD, PharmD)

  • 15 or more years of pharmaceutical / biotechnology industry experience

  • 10 or more years of Medical Affairs experience, with prior launch experience and a minimum of 5 years of people management experience within industry

  • Possess scientific credibility and enterprise thinking to provide proactive solutions to complex enterprise needs, with a sophisticated understanding of regulatory, medical practice, and economic environments impacting Roche/Genentech globally and within the US.

  • Demonstrate superb collaboration, influencing, and communication skills to build partnerships with cross-functional commercial, development, and global peers.

  • Show a successful track record of collaborating, coaching, and influencing outcomes in complex organizations and projects, embracing an agile mindset and the new digital healthcare landscape.

  • Understand corporate legal and compliance groups, finance, and large-scale budget development, management, and administration, with the ability to establish relationships and identify the needs of patients, providers, and payers.

Travel Requirements

The position is located in South San Francisco and may require up to an additional 35% time traveling.

The expected salary range for this position based on the primary location of South San Francisco, CA is $269,700 - 591,800. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at the link provided below.

Benefits

Relocation benefits are available for this job posting.

Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws.

If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.

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