Position Information
| Posting Number |
PG191602PD |
| Position Number |
00111796 |
| Position Type |
Post Doc |
| FLSA |
|
Departmental Information
| Department ID |
196001 - Department of Population Health and Pathobiology |
| Department |
196001 - Department of Population Health and Pathobiology |
| Job City & State |
Raleigh, NC |
Position Overview
| Essential Job Duties |
The research project will be part of a team focused on developing recombinant infectious laryngotracheitis virus (
ILTV)-based vaccines using a
CRISPR/Cas9 approach, as well as infectious bronchitis virus (
IBV) vaccines using a reverse genetics system.
In addition, the project aims to establish reverse genetics-based infectious clones for other poultry viruses to support vaccine design and the development of effective vaccination strategies.
The work will also involve evaluating
in vivo vaccine protection and efficacy mechanisms, including animal inoculation, sample collection, data analysis, and interpretation of results.
Duties and Responsibilities:
*
Molecular virology tools: Design, plan, and execute research experiments focused on
CRISPR/Cas9 gene editing of
DNA viruses and the use of reverse genetics systems to edit
RNA viruses, including knockout of viral genes and subsequent evaluation of virus-host interactions. Apply advanced recombinant techniques to study and edit viral genomes.
*
Quantification of viral titers, infectivity, and neutralization titers: Design and develop viral titration and infectivity protocols, and develop neutralization assays and other serum-based fluorescent assays.
*
Vaccine protection studies: Evaluate the vaccine protection and/or efficacy of vectored and attenuated vaccines.
*
Data analysis, interpretation, and reporting: Perform statistical analyses of experimental data, interpret findings, and contribute to manuscript preparation, presentations, and research reports. Maintain detailed research records, datasets, and methodological documentation in accordance with project, institutional, and regulatory requirements.
*
Bioinformatics and transcriptomics: Perform bioinformatics analyses, including
RNA-seq data processing and interpretation.
*
Team collaboration and training: Work closely with team members and contribute to the training and mentoring of graduate students.
|
| Other Work/Responsibilities |
Assist Dr. Reddy in establishing, organizing, and maintaining the molecular virology laboratory. |
| Wolfpack Perks and Benefits |
As a Pack member,
you belong here, and can enjoy
exclusive perks
designed to enhance your personal and professional well-being. As you consider this opportunity, we encourage you to review our
Employee Value Propositionand learn more about what makes NC State the best place to learn and work for everyone.
What we offer:
- Medical, Dental, Vision, Retirement and Leave
- Faculty and Staff Assistance Program
- Enhance your career with LEAD courses
Attend non-revenue generating sporting events for free.
Attain Work-life balance with our
Childcare benefits,
Wellness & Recreation Membership, and
Wellness Programs that aim to build a thriving wolfpack community.
Disclaimer: Perks and Benefit eligibility is based on Part-Time or Full-Time Employment status. Eligibility and Employer Sponsored Plans can be found within each of the links offered. |
Requirements and Preferences
| Work Schedule |
Mon-Fri (8am-5pm) |
| Department Required Skills |
N/A |
| Preferred Years Experience, Skills, Training, Education |
- Experience working with gene editing molecular virology tools such as the reverse genetics system and the CRISPR/Cas9 system, with strong hands-on expertise in molecular cloning strategies.
- Proficiency in applying fluorescent microscopy methodologies to study virus-host interactions.
- Experience using advanced DNA and RNA sequencing approaches to characterize circulating viral strains and analyze differential gene expression.
- Experience working with poultry research facilities, including isolators and/or floor-pen systems.
- Excellent writing and verbal communication skills in English.
|
| Required License or Certification |
N/A |
| Valid NC Driver's License required? |
No |
| Commercial Driver's License Required? |
No |
Recruitment Details
| Anticipated Hiring Range |
$58,656 |
| If you anticipate multiple hires from this search, please indicate how many |
|
Applicant Information
| Quick Link |
https://jobs.ncsu.edu/postings/226037 |
| EEO |
NC State University is an equal opportunity employer. All qualified applicants will receive equal opportunities for employment without regard to age, color, disability, gender identity, genetic information, national origin, race, religion, sex (including pregnancy), sexual orientation, and veteran status. The University encourages all qualified applicants, including protected veterans and individuals with disabilities, to apply. Individuals with disabilities requiring disability-related accommodations in the application and interview process are welcome to contact 919-513-0574 to speak with a representative of the Office of Equal Opportunity.
If you have general questions about the application process, you may contact Human Resources at (919) 515-2135 or
workatncstate@ncsu.edu.
Final candidates are subject to criminal & sex offender background checks. Some vacancies also require credit or motor vehicle checks. Degree(s) must be obtained prior to start date in order to meet qualifications and receive credit.
NC State University participates in E-Verify. Federal law requires all employers to verify the identity and employment eligibility of all persons hired to work in the United States. |
|
North Carolina State University
$58,656
Dec 20, 2025