2026 Summer Intern - Computational Biology and Medicine - Immunology

2026 Summer Intern - Computational Biology and Medicine - Immunology

Advances in AI, data, and computational sciences are transforming drug discovery and development. Roche's Research and Early Development organisations at Genentech (gRED) and Pharma (pRED) have demonstrated how these technologies accelerate R&D, leveraging data and novel computational models to drive impact. The new Computational Sciences Center of Excellence (CoE) is a strategic, unified group whose goal is to harness this transformative power of data and Artificial Intelligence (AI) to assist our scientists in both pRED and gRED to deliver more innovative and transformative medicines for patients worldwide.

The Immunology and CVRM team within the CS-CoE Computational Biology and Medicine department is seeking a highly motivated Summer Intern with a strong background in computational biology and immunology as well as deep experience with single-cell RNA-seq of granular cell states.

This internship position is located in New York City, On - Site.

The Opportunity

The internship focuses on an integrative analysis of scRNA-seq data taken from IBD patient biopsies and blood samples. The core goal is to uncover precursor cell states that drive disease pathology and identify their stimulating cues through comparative analysis of transcriptional programs in patients and healthy individuals. The insights generated will directly inform therapeutic targets and development discovery strategies.

• Execute end-to-end processing for high-resolution scRNA-seq analysis (e.g., Metacells, SEACells), including QC, doublet removal, cell-type annotation, multi-layered clustering, and deep immunological characterization.

• Integrate the scRNA-seq findings with in-vitro stimulation datasets to identify key drivers of cell-states and their regulatory mechanisms.

• Infer differentiation trajectories across blood and tissue cell states to explain molecular patient-to-patient heterogeneity and response to treatment.

Program Highlights

• Intensive 12-week, full-time (40 hours per week) paid internship.

• Program start dates are in May/June 2026.

• A stipend, based on location, will be provided to help alleviate costs associated with the internship.

• Ownership of challenging and impactful business-critical projects.

• Work with some of the most talented people in the biotechnology industry.

Who You Are (Required)

Required Education

• Must be pursuing a PhD (enrolled student).

Required Majors: Computational Biology, Bioinformatics, Immunology, Biomedical Engineering, Computer Sciences, or a related field.

Required Skills:

• Proficiency in R or Python, and multidimensional data analysis.

• Strong understanding of immunology and single-cell analysis methods.

• Ability to translate complex analyses to interpretable biological insights is critical for success in this role.

• Detail-oriented, critical thinker, goal-driven, and dedicated to delivering high-quality results.

Preferred Knowledge, Skills, and Qualifications

• Excellent communication, collaboration, and interpersonal skills.

• Complements our culture and the standards that guide our daily behavior & decisions: Integrity, Courage, and Passion.

• Experience with high resolution scRNA-seq analysis (e.g. Metacells, SEACells),

• Knowledge of autoimmune diseases, such as Inflammatory Bowel Disease, is highly desirable.

Relocation benefits are not available for this job posting.

The expected salary range for this position based on the primary location of New York is $50.00 per hour.Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. This position also qualifies for paid holiday time off benefits.

Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws.

If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.