Staff Scientist I - MaineHealth Institute for Research

Description

Professional - Nonclinical
Req #: 82590

This position is for applicants interested in joining the Yanming Li Lab of the MaineHealth Institute for Research (MHIR). Dr. Li's laboratory is at the forefront of vascular biology and cardiovascular disease research, through innovative studies on the molecular and cellular mechanisms of aortic aneurysms and dissections. Our focus lies in uncovering the genetic, epigenetic and metabolic switches that govern aortic disease initiation and progression. By leveraging single-cell and multi-omics methodologies, we aim to understand how genomic alterations influence epigenetic regulation, drive dynamic cellular responses, and reveal novel therapeutic targets for aortic diseases.

The Role:

The Staff Scientist I is expected to investigate the molecular mechanisms of aortic aneurysms and dissection-associated genetic variants underlying the initiation and development of TAAD, ultimately paving the way for the development of treatments. The successful candidate will perform integrative analyses of GWAS, scATAC-seq, Cut&Run-seq, chromatin conformation (Hi-C), and scRNA-seq data to pave the way for the development of new treatments.

Successful candidates will have:

• PhD in Bioinformatics or Genomics
• At least five years of postdoctoral training
• Demonstrated experience in population genetics and epigenetics
• Proven proficiency in single-cell and multi-omics integration analysis

The Staff Scientist I role assists in conducting a variety of research activities:

• Managing grants or projects
• Writing grants and obtaining funding for major research projects assigned by the Principal Investigator
• Writing project reports
• Monitoring project budgets
• Mentoring Learners, as assigned
• Ensuring compliance with all state and federal regulations pertaining to safety, ethical conduct of research, financial reporting to funding agencies.

This position is a fully onsite role at our Scarborough, ME research facility.

The MaineHealth application, a cover letter and a resume or CV are all required elements for application to this position.

Learn more about the MaineHealth Institute for Research in this short video!

Knowledge Skills And Abilities:

1. Education: Doctoral Degree in relevant biomedical discipline required. Completion of post-doctoral training required.

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Additional Information

If you have questions about this role, please contact sharon.nightingale@mainehealth.org